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Loaisis Some species of Chrysops, C. Silacea and C. Dimidiata in tropical West Africa (Sierra Leone to Ghana and Nigeria), and C. Distinctipennis in Central Africa (southern Sudan and Uganda), will transmit Loa loa to humans (Fig. The microfilaria is taken up by the female horsefly from the peripheral blood during the day (diurnal periodicity). Development through two larval stages (Fig. 15) occurs in the thoracic muscles of the vector for 10 to 12 days before migrating to the proboscis and piercing the labial membrane to reach a new host at a subsequent blood feed.

41 26 Distribution of yellow fever. { Dengue rash. MEDICAL SIGNIFICANCE Diagnosis is made by serological methods. Treatment is generally symptomatic; haemorrhagic forms will require intravenous fluids. Some of these infections may respond to treatment with ribavirin. Pilote Imprimante Hp F2280. Production of vaccines for arbovirus diseases is generally difficult, although very effective vaccines exist to prevent Japanese encephalitis. Yellow fever Yellow fever (Fig.

41) is caused by an arbovirus transmitted by several culicine (Aedes) species, particularly the notorious urban vector Aedes aegypti (Fig. 27 MOSQUITOES Filariasis Fig. 44 Typical Aedes aegypti breeding site. Note larvae present in the gulley. Imposed by health inspectors on the owner of a property on which mosquitoes are found breeding. A yellow card (Fig. 45) fixed to the building shows that it was free from potential vector mosquitoes on inspection.

Wuchereria bancrofti and Brugia malayi have a nocturnal periodicity, being found in the peripheral blood of the host in the infective microfilarial form at night, whereupon they are taken up by mosquitoes feeding nocturnally.

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